Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Tert-butylcyclohexane-1-carboxylic acid → n-((5s)-3-(4-(1-{4-t-Butylcyclohexylcarbonyl}-1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Tert-butylcyclohexane-1-carboxylic acid | HCID 136759 | — |
| 반응물 | N-((5S)-3-(4-(1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide | HCID 20638827 | — |
| 생성물 | n-((5s)-3-(4-(1-{4-t-Butylcyclohexylcarbonyl}-1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide | HCID 57235224 | — |
반응 단계
Using an analogous procedure to that described in Example 20, the TFA salt of Example 2 was reacted with 4-tert-butylcyclohexanecarboxylic acid in place of N-acetylglycine, to give the title compound. Yield=208 mg, 58%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06271383B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-f5e914135cfd4454a320f3dca5b9378f |
| 출처 메모 | uspto-grants-2001_08 |