Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Carbon Disulfide → n-Decyl (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Carbon Disulfide | HCID 6348 | — |
| 반응물 | 1-Bromodecane | HCID 8173 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline | HCID 13375506 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | n-Decyl (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate | HCID 13392983 | — |
반응 단계
In the same manner as described in Example 29 by using (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (2.02 g), triethylamine (1.67 ml), CS2 (0.72 ml), n-decyl bromide (2.65 g) and dimethylsulfoxide (10 ml), there is prepared the title compound (2,48 g, 59%) as colorless needles, m.p. 115°-118° C. (recrystallized from ether-n-hexane), [α]D20 +113.0° (c=1.0, methanol); NMR (CDCl3, δ): 0.95 (m, 3H, --CH3); Mass m/e: 418 (M+), 244 (M+ --C10H21SH).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04612317 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-fe5e6cce12ce49b6a922bf6da1fef0e1 |
| 출처 메모 | uspto-grants-1986_09 |