Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Methylimidazole → 3-Methyl-1-[2-[4-((methylsulfonyl)amino)phenyl]-2-oxoethyl]-1H-imidazolium chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Methylimidazole | HCID 1390 | — |
| 반응물 | Methanesulfonamide, N-[4-(2-chloroacetyl)phenyl]- | HCID 116629 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3-Methyl-1-[2-[4-((methylsulfonyl)amino)phenyl]-2-oxoethyl]-1H-imidazolium chloride | HCID 86741031 | — |
반응 단계
Heat a mixture of 160 g (0.646 mole) of N-[4-(2- chloro-1-oxoethyl)phenyl]methanesulfonamide, 55.7 g (0.678 mole) of 1-methyl-1H-imidazole and 2.1 L of acetonitrile at reflux for about 16 hours. Cool the mixture to room temperature and collect the solid and wash with 2 L of acetonitrile. Drying provides the title compound, which may be recrystallized from aqueous ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04613609 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-54ad68dcd9fd4af29864d76629da11a9 |
| 출처 메모 | uspto-grants-1986_09 |