Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Propynenitrile → 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Propynenitrile | HCID 14055 | — |
| 반응물 | (3Z)-3-diazo-1H-indol-2-one | HCID 136455454 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonitrile | HCID 135735621 | — |
반응 단계
6.0 g (0.04 mole) of 3-diazooxindole and 2.2 g (0.045 mole) of cyanoacetylene are taken up in benzene (250 ml) and refluxed overnight under N2. The mixture is cooled and the beige-colored precipitates are filtered off. The crude product is dried in a vacuum oven at room temperature for 3 hours. Yield: 5.2 g, m.p. 302°-304°. Percent yield: 65.6.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04128644 |
| 출처 데이터셋 | uspto-grants-1978_12 |
| ORD ID | ord-17badc783a4f4776bd16b92132f8856e |
| 출처 메모 | uspto-grants-1978_12 |