Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
m-Chloroperbenzoic acid → 4-(4-Methoxyphenyl)pyridine 1-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 반응물 | 4-(4-Methoxyphenyl)pyridine | HCID 603813 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 4-(4-Methoxyphenyl)pyridine 1-oxide | HCID 57672026 | 91.1% |
반응 단계
A solution of 4-(4-methoxyphenyl)pyridine (5.68 g) and metachloroperbenzoic acid (70%, 11.34 g) in chloroform is stirred for 2.5 hours at room temperature, concentrated under reduced pressure and purified by chromatography over silica gel (eluent dichloromethane/methanol from 100/0 to 90/10) to give 5.62 g of 4-(4-methoxyphenyl)pyridine 1-oxide used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08076329B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-f738d9a8a70f4f0b924fb6511fffda6b |
| 출처 메모 | uspto-grants-2011_12 |