Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(Azidomethyl)-2-methylpyrimidine → (2-Methylpyrimidin-5-yl)methanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(Azidomethyl)-2-methylpyrimidine | HCID 54595022 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | (2-Methylpyrimidin-5-yl)methanamine | HCID 21294601 | — |
반응 단계
A mixture of 5-(azidomethyl)-2-methylpyrimidine (2.0, 13.4 mmol) in ethyl acetate (100 mL), and 10% Pd—C (4.0 g) was stirred under H2 (1 atm) for 1.5 hr. The catalyst was filtered off and filtrate was concentrated in vacuo to afford a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08076345B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-b72392e4d85f48d1980ff7238dcb0187 |
| 출처 메모 | uspto-grants-2011_12 |