Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Bis(trifluoromethyl)benzoic acid → N-((1RS,2SR)-2-Pyrrolidin-1-yl-cyclohexyl)-2,4-bis-trifluoromethyl-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Bis(trifluoromethyl)benzoic acid | HCID 141752 | — |
| 반응물 | cis-2-Pyrrolidin-1-yl-cyclohexylamine dihydrochloride | HCID 66680564 | — |
| 생성물 | N-((1RS,2SR)-2-Pyrrolidin-1-yl-cyclohexyl)-2,4-bis-trifluoromethyl-benzamide | HCID 76682967 | — |
반응 단계
The title compound, white solid, MS: m/e=409.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclohexylamine dihydrochloride (intermediate F) and 2,4-bis(trifluoromethyl)benzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08080541B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-0ca50ce8347b43a1b4349491bec9f3be |
| 출처 메모 | uspto-grants-2011_12 |