Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,4-Dibromo-2-butanol → N-[(1RS,2SR)-2-(3-Hydroxy-pyrrolidin-1-yl)-cyclopentyl]-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,4-Dibromo-2-butanol | HCID 29570 | — |
| 반응물 | N-((1RS,2SR)-2-Amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide | HCID 66681196 | — |
| 생성물 | N-[(1RS,2SR)-2-(3-Hydroxy-pyrrolidin-1-yl)-cyclopentyl]-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide | HCID 66682712 | — |
반응 단계
The title compound, colorless gum, MS: m/e=419.2 [(M+H)+], was prepared in accordance with the general method of example 10 from N-((1RS,2SR)-2-amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate O) and 1,4-dibromo-2-butanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08080541B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-5abd4a8454c44caf936c56b99252595e |
| 출처 메모 | uspto-grants-2011_12 |