Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium periodate → 7-Acetoxy-8-methoxycoumarin-6-acetaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium periodate | HCID 516896 | — |
| 반응물 | 7-Acetoxy-6-allyl-8-methoxycoumarin | HCID 21814501 | — |
| 촉매 | Osmium Tetroxide | HCID 30318 | — |
| 용매 | Water ethylacetate | HCID 22728543 | — |
| 생성물 | 7-Acetoxy-8-methoxycoumarin-6-acetaldehyde | HCID 53767256 | — |
반응 단계
A solution of 0.274g. (0.001 mole) of 7-acetoxy-6-allyl-8-methoxycoumarin in 10 ml. EtOAc/water, 1:1 was treated with 0.8 g. (.0033 mole) of potassium periodate and 0.5 ml. of a 10% aqueous solution of osmium tetroxide (10 mg. OsO4 /ml H2O). The reactants were stirred at 25° for 5.0 hours. The organic layer was separated, and the aqueous phase was further extracted with ethyl acetate. The organic extracts were combined, dried over sodium sulfate, and evaporated to yield pure 7-acetoxy-8-methoxycoumarin-6-acetaldehyde as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04130568 |
| 출처 데이터셋 | uspto-grants-1978_12 |
| ORD ID | ord-114648409cd6424fb94fc756031f3ca9 |
| 출처 메모 | uspto-grants-1978_12 |