Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → Ethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-phenoxycarbonyloxy-1-isoindolinone | HCID 23343637 | — |
| 생성물 | Ethylamine | HCID 6341 | — |
| 생성물 | 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-ethylaminocarbonyloxy-isoindolin-1-one | HCID 22754760 | — |
반응 단계
Following the procedure of Example 1 but starting with 2-(7-chloro-1,8-naphthyridin-2-yl)-3-phenoxycarbonyloxy-isoindolin-1-one (8.6 g.) and a 33% (w/v) aqueous solution of ethylamine (d = 0.92; 9 cc.) in acetonitrile (200 cc.), 2-(7-chloro-1,8-naphthyridin-2-yl)-3-ethylaminocarbonyloxy-isoindolin-1-one (4.1 g.), melting at 212°-215° C., is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04131674 |
| 출처 데이터셋 | uspto-grants-1978_12 |
| ORD ID | ord-9ae1e3ea4d8e4c91a797088a3323a205 |
| 출처 메모 | uspto-grants-1978_12 |