Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 2,3,4,9-tetrahydro-1H-beta-carbolin-6-ol hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Serotonin Hydrochloride | HCID 160436 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2,3,4,9-tetrahydro-1H-beta-carbolin-6-ol hydrochloride | HCID 22018498 | — |
반응 단계
To a solution of 3-(2-amino-ethyl)-1H-indol-5-ol hydrochloride (10.0 g) in 450 mL of absolute ethanol was added 1.6 g of paraformaldehyde and 5.4 mL of glacial acetic acid. The mixture was heated to reflux for 1.5 h then allowed to cool to rt. The white precipitate so formed was collected by filtration and dried under vacuum to yield 5.9 g of 2,3,4,9-tetrahydro-1H-β-carbolin-6-ol hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07084154B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-94519c87f60641e69754c5d68bb615e7 |
| 출처 메모 | uspto-grants-2006_08 |