참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Sarcosine | HCID 1088 | — |
| 반응물 | 6-Fluoroisatoic anhydride | HCID 2783057 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 6-Fluoro-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione | HCID 22914547 | — |
반응 단계
7.2 g (0.04 mol) of 6-fluoroisatoic acid anhydride and 3.9 g (0.044 mol) of sarcosine are added to 10 ml of dimethyl sulphoxide and the mixture is heated at 100° C. for 30 minutes. After cooling and diluting with 15 ml of water, the separated substance is filtered off. After drying, there is obtained 6-fluoro-3,4-dihydro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dione of melting point 214°-217° C. (decomposition).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04346034 |
|---|
| 출처 데이터셋 | uspto-grants-1982_08 |
|---|
| ORD ID | ord-b453a709e7894cdba30ef73ac2690c5e |
|---|
| 출처 메모 | uspto-grants-1982_08 |
|---|
