Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 4-(Bromomethyl)-3-chlorobenzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 3-Chloro-p-toluonitrile | HCID 88894 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 4-(Bromomethyl)-3-chlorobenzonitrile | HCID 13042093 | — |
반응 단계
A mixture of 3-chloro-4-methyl-benzonitrile (30.0 g, 0.2 mol), N-bromosuccinimide (36.0 g, 0.21 mol) and benzoyl peroxide (100 mg) in 600 mL of CCl4 was refluxed with illumination for 72 h. N-Bromosuccinimide (5.0 g) was added and the reaction was continued for an additional 24 h. The mixture was cooled, filtered and evaporated. Recrystallization from heptane gave pure 2-chloro-4-cyanobenzyl bromide: yield 24.5 g; mp 83°-85° C. Anal. calcd for C8H5BrClN; C, 41.69; H, 2.19; N, 6.07. Found: C, 41.48; H, 1.80; N, 5.76. ##STR27##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04347177 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-e36a76c8198e44b5994e1489848c4c62 |
| 출처 메모 | uspto-grants-1982_08 |