Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-5-ethylpyrimidine → (3R,4S)-Cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-3-fluoro-piperidin-4-yl]-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| 반응물 | HCID 68289942 | HCID 68289942 | — |
| 생성물 | (3R,4S)-Cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-3-fluoro-piperidin-4-yl]-amine | HCID 68290756 | — |
반응 단계
The title compound is prepared from cyclopropyl-[(3R,4S)-3-fluoro-piperidin-4-yl]-carbamic acid tert-butyl ester and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described for Intermediate 73.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822471B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-4f4240851600414389af3338dc926741 |
| 출처 메모 | uspto-grants-2014_09 |