Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Benzofuran-2-sulfonyl chloride → Tert-butyl {4-[({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}thio)methyl]pyridin-2-yl}carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Benzofuran-2-sulfonyl chloride | HCID 2795172 | — |
| 반응물 | Tert-butyl (4-(((2-amino-4-chlorophenyl)thio)methyl)pyridin-2-yl)carbamate | HCID 68074576 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | Tert-butyl {4-[({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}thio)methyl]pyridin-2-yl}carbamate | HCID 68074730 | 56% |
반응 단계
Following General Procedure B, the title compound (555 mg, 56%) was prepared from tert-butyl (4-(((2-amino-4-chlorophenyl)thio)methyl)pyridin-2-yl)carbamate (667 mg, 1.827 mmol) and benzofuran-2-sulfonyl chloride (396 mg, 1.827 mmol) in pyridine (10 ml).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822530B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-05ff11b4bb284f25bcab7ada82bcefd5 |
| 출처 메모 | uspto-grants-2014_09 |