Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → HCID 66968119, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Thiophene | HCID 8030 | — |
| 반응물 | 1-Phenylcyclohexene | HCID 13043 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Hydrogen Bromide | HCID 260 | — |
| 생성물 | HCID 66968119 | HCID 66968119 | — |
반응 단계
Phenyl cyclohexene (50 mg) and thiophene (100 mg) were dissolved in 33% HBr in acetic acid (0.5 mL). The mixture was stirred at room temperature over night. Tlc indicated full conversion of the starting material. Dichloromethane (10 mL) was added. The organic phase was washed with saturated NaHCO3 (3×10 mL), dried Na2SO4 and concentrated in vacuo. The desired product was afforded after flash chromatography (eluent: dichloromethane). Yield: 39 mg. LC/MS purity (UV/MS): 100/90%, Rt 6.22 min. M+1: 243
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822548B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-7c2b84a7b779425e99164e43cf496820 |
| 출처 메모 | uspto-grants-2014_09 |