Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(Oct-1-ynyl)-1H-indole → 2,2,2-Trifluoro-1-(4-octylindolin-1-yl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(Oct-1-ynyl)-1H-indole | HCID 66726751 | — |
| 반응물 | 2,2,2-Trifluoro-1-(4-(oct-1-ynyl)indolin-1-yl)ethanone | HCID 86661816 | — |
| 생성물 | 2,2,2-Trifluoro-1-(4-octylindolin-1-yl)ethanone | HCID 86661815 | 77% |
반응 단계
When the product of Step B was substituted for 5-(oct-1-ynyl)-1H-indole in Example 3, Step B, the identical process afforded the title compound in 77% yield, as colourless oil. 1H-NMR (CDCl3) 0.86 (m, 3H); 1.28 (m, 10H); 1.57 (m, 2H); 2.54 (tr, 2H, J=8 Hz); 3.17 (tr, 2H, J=8.3 Hz); 4.27 (tr, 2H, J=8 Hz); 6.97 (d, 1H, J=7.6 Hz); 7.2 (tr, 1H, J=7.9 Hz); 8.04 (d, 1H, J=8.1 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09181182B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-0f794ef260a44a3084f45e4bfafe5218 |
| 출처 메모 | uspto-grants-2015_11 |