Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isocyanic acid, p-methoxybenzyl- → 4-(5-Amino-2-(pyridin-3-yl)thiazolo[5,4-d]pyrimidin-7-yl)-n-(4-methoxybenzyl)piperazine-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isocyanic acid, p-methoxybenzyl- | HCID 187910 | — |
| 반응물 | 7-(Piperazin-1-yl)-2-(pyridin-3-yl)thiazolo[5,4-d]pyrimidin-5-amine | HCID 50942056 | — |
| 생성물 | 4-(5-Amino-2-(pyridin-3-yl)thiazolo[5,4-d]pyrimidin-7-yl)-n-(4-methoxybenzyl)piperazine-1-carboxamide | HCID 66758627 | 40% |
반응 단계
This compound was prepared from 7-(piperazin-1-yl)-2-(pyridin-3-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-methoxybenzyl isocyanate in a yield of 40%, according to the procedure for the synthesis of example 42.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09193741B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-e32f2e7bf5aa41039490bba2ed98f4aa |
| 출처 메모 | uspto-grants-2015_11 |