Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Methylcyclopropane-1-sulfonamide → 1-Benzoylcyclopropane-1-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Methylcyclopropane-1-sulfonamide | HCID 21889814 | — |
| 반응물 | 1-Benzoyl-N-tert-butylcyclopropane-1-sulfonamide | HCID 21889830 | — |
| 생성물 | 1-Benzoylcyclopropane-1-sulfonamide | HCID 21889794 | 87% |
반응 단계
This compound, Example 6,1-benzoylcyclopropyl-sulfonamide, was obtained in 87% yield from N-tert-butyl(1-benzoyl)cyclopropylsul-fonamide using the procedure described for the synthesis of 1-Methylcyclopropylsulfonamide, followed by recrystallization from the minimum amount of EtOAc in hexane: 1H NMR (DMSO-d6) δ 1.39 (m, 2H), 1.61 (m, 2H), 7.22 (s, 2H), 7.53 (t, J=7.6 Hz, 2H), 7.65 (t, J=7.6 Hz, 1H), 8.06 (d, J=8.2 Hz, 2H); 13C NMR (DMSO d6) δ 12.3, 48.4, 128.1, 130.0, 133.4, 135.3, 192.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07135462B2 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-070a481e14ef4de7bf9500bde3b56a0e |
| 출처 메모 | uspto-grants-2006_11 |