Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiophenol → N-{4-[2-Amino-3,5-dicyano-6-(phenylsulphanyl)-4-pyridinyl]phenyl}acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiophenol | HCID 7969 | — |
| 반응물 | Malononitrile | HCID 8010 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide | HCID 33296 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-{4-[2-Amino-3,5-dicyano-6-(phenylsulphanyl)-4-pyridinyl]phenyl}acetamide | HCID 12016387 | — |
반응 단계
19 g (0.09 mol) of N-[4-(2,2-dicyanovinyl)phenyl]acetamide, 5.95 g (0.09 mol) of malononitrile and 9.91 g (0.09 mol) of thiophenol are initially charged in 120 ml of ethanol, and 0.4 ml of triethylamine are added. The mixture is stirred at reflux for 2 h, during which the product crystallizes. After cooling, the product is filtered off with suction and dried under reduced pressure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07135486B1 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-9db1f65e28f44eb980bc6e416322f632 |
| 출처 메모 | uspto-grants-2006_11 |