Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Methyl-1-piperazine)propan-1-ol → n-[(5s)-3-(3-(4-Methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5h-dibenzo[a,c]cyclohepten-5-yl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Methyl-1-piperazine)propan-1-ol | HCID 79208 | — |
| 반응물 | N-Acetylcolchicinol | HCID 97865 | — |
| 생성물 | n-[(5s)-3-(3-(4-Methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5h-dibenzo[a,c]cyclohepten-5-yl]acetamide | HCID 9848717 | 22% |
반응 단계
Using an analogous procedure to that described for Example 7, N-acetyl-colchicinol was reacted with 4-(3-hydroxypropyl)-1-methylpiperazine to give N-[(5S)-3-(3-(4-methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-5-yl]acetamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07135502B1 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-6dd86504269c4126a9a6f0039fa5a4eb |
| 출처 메모 | uspto-grants-2006_11 |