Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → L-Glutamic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | L-Glutamic acid di-tert-butyl ester | HCID 208637 | — |
| 반응물 | 2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate | HCID 9857522 | — |
| 반응물 | Succinimidyl hexadecandioate | HCID 131727748 | — |
| 생성물 | L-Glutamic Acid | HCID 33032 | — |
반응 단계
This compound was prepared in analogy with example 4, via reaction of L-Glu(OtBu)-OtBu with succinimidyl hexadecandioate followed by activation with TSTU, coupling with Des(B30) human insulin and deprotection by TFA. LCMS 6130.8, calculated 6132.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08828923B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-8a8b5a6e191740d29489d0fdf6c12a18 |
| 출처 메모 | uspto-grants-2014_09 |