Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutyl chloroformate → (R)-(2-adamantyl) 3-(isobutoxycarbonylamino)pyrrolidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutyl chloroformate | HCID 62365 | — |
| 반응물 | (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt | HCID 67155574 | — |
| 생성물 | (R)-(2-adamantyl) 3-(isobutoxycarbonylamino)pyrrolidine-1-carboxylate | HCID 52942175 | — |
반응 단계
The title compound was prepared from (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt and isobutyl chloroformate following a procedure analogous to that described in Example 3 Step 2. LC-MS Method 1 tR=2.1 min, m/z=365; 1H NMR (CDCl3) 0.97 (d, 6H), 1.58 (d, 2H), 1.70-2.05 (14H), 2.18 (m, 1H), 2.80 (1H), 3.29 (dd, 1H), 3.53 (m, 2H), 3.70 (m, 1H), 3.84 (m, 1H), 4.28 (1H), 4.80 (1H), 4.83 (s, 1H)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08828985B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-cdf0962cd05a4fa2998e80064efa07cf |
| 출처 메모 | uspto-grants-2014_09 |