Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 3-amino-4-iodobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-Amino-4-iodobenzoic acid | HCID 11807503 | — |
| 생성물 | Methyl 3-amino-4-iodobenzoate | HCID 21628210 | — |
반응 단계
3-Amino-4-iodobenzoic acid (13.35 g, 50.8 mmol) was added to MeOH (150 mL) and SOCl2 (4.8 mL, 65.8 mmol, 1.3 equivalent) was added. The mixture was refluxed for 3 h and then volatiles were removed under reduced pressure. The residue was co-evaporated three times with MeOH and dried in vacuo (15.23 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07141574B2 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-b5a7e02008f34cf0bac20ad17989f0b4 |
| 출처 메모 | uspto-grants-2006_11 |