Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Phenylethyl)thiourea → 3-Nitro-5-[2-(phenethylamino)-4-thiazolyl]pyrocatechol hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Phenylethyl)thiourea | HCID 735845 | — |
| 반응물 | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | 3-Nitro-5-[2-(phenethylamino)-4-thiazolyl]pyrocatechol hydrobromide | HCID 21459205 | — |
반응 단계
A suspension of 13.8 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone is treated with 9.0 g of 1-(phenethyl)-2-thiourea in 150 ml of n-butanol and the mixture is heated to boiling under reflux for 3 hours. After cooling to room temperature, the crystals are filtered under suction and crystallized from n-butanol. There is obtained 3-nitro-5-[2-(phenethylamino)-4-thiazolyl]pyrocatechol hydrobromide of m.p. 249°-251°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05705703 |
| 출처 데이터셋 | uspto-grants-1998_01 |
| ORD ID | ord-bde888d1d961431a9319617657e06e89 |
| 출처 메모 | uspto-grants-1998_01 |