Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2-Methoxyphenyl)piperazine → HCID 11463465, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| 반응물 | 2-((2E)-4-chlorobut-2-en-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione | HCID 5709374 | — |
| 반응물 | Trans-4-[4-(2-methyloxyphenyl)piperazinyl]-2-buten-1-yl-amine | HCID 19917461 | — |
| 생성물 | HCID 11463465 | HCID 11463465 | 85.6% |
반응 단계
Trans-4-[4-(2-methyloxyphenyl)piperazinyl]-2-buten-1-yl-amine: according to the method of Example 5, N-(trans-4-chloro-2-buten-1-yl)phthalimide was reacted with 1-(2-methyloxyphenyl)piperazine to obtain N-{4-[4-(2-methyloxy-phenyl)piperazinyl]-trans-2-buten-1-yl}phthalimide, which was then reacted with hydrazine hydrate. Yield: 85.6%, hydrochloride mp: 178-180° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829001B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-e3b2767709a643edab482f09656c61d0 |
| 출처 메모 | uspto-grants-2014_09 |