Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Carbonate → HCID 67362076, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | Trans-4-[4-(2-methyloxyphenyl)piperazinyl]-2-buten-1-yl-amine | HCID 19917461 | — |
| 반응물 | HCID 87370277 | HCID 87370277 | — |
| 생성물 | HCID 67362076 | HCID 67362076 | 87.5% |
반응 단계
According to the method of Example 7, trans-4-[4-(2-methyloxyphenyl)piperazinyl]-2-buten-1-yl-amine and benzoxazolin-2-one-6-carbonyl chloride were subjected to acylation in the presence of sodium carbonate to obtain the product. Yield: 87.5%. mp: 200-202° C. 1HNMR (ppm, DMSO-d6) δ: 2.50 (m, 4H), 2.96 (s, br., 4H), 3.31 (m, 2H), 3.75 (s, 3H), 3.89 (t, 2H), 5.62-5.67 (m, 2H), 6.86 (m, 2H), 6.91 (m, 2H), 7.14 (d, J=8.2 Hz, 1H), 7.73-7.77 (m, 2H), 8.63 (t, J=5.6 Hz, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829001B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-a994ecd3eef74b01bec51d632596988c |
| 출처 메모 | uspto-grants-2014_09 |