Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl (2S)-5-{[(benzyloxy)carbonyl]amino}-2-{[(tert-butoxy)carbonyl]amino}pentanoate → (S)-tert-Butyl 5-amino-2-((tert-butoxycarbonyl)amino)pentanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl (2S)-5-{[(benzyloxy)carbonyl]amino}-2-{[(tert-butoxy)carbonyl]amino}pentanoate | HCID 10047875 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (S)-tert-Butyl 5-amino-2-((tert-butoxycarbonyl)amino)pentanoate | HCID 7006667 | — |
반응 단계
Mix N-t-butyloxycarbonyl-N5 -benzyloxycarbonyl-ornithine, t-butyl ester (2.0 g, 5.0 mmol) and 10% palladium/carbon (0.5 g) in 95% ethanol (40 mL). Hydrogenate at room temperature at atmospheric pressure. Filter and evaporate the filtrate in vacuo to give N-t-butyloxycarbonyl-ornithine, t-butyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05710324 |
| 출처 데이터셋 | uspto-grants-1998_01 |
| ORD ID | ord-94ac1031f51e40399e2981165d814800 |
| 출처 메모 | uspto-grants-1998_01 |