Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-(Trifluoromethoxy)benzenesulphonyl chloride → N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-trifluoromethoxy-benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-(Trifluoromethoxy)benzenesulphonyl chloride | HCID 523102 | — |
| 반응물 | (2-Amino-5-bromophenyl)(pyridin-4-yl)methanone | HCID 13549724 | — |
| 생성물 | N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-trifluoromethoxy-benzenesulfonamide | HCID 10413664 | — |
반응 단계
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-Amino-5-bromo-phenyl)-pyridin-4-yl-methanone and 130 mg of 4-Trifluoromethoxy-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 7.23 (d, 2H, J=8.0 Hz), 7.45 (m, 3H), 7.71 (m, 2H), 7.85 (d, 2H, J=8.8 Hz), 8.85 (d, 2H, J=6.4 Hz), 10.23 (s, 1H). MS: m/z 502.9 (M++1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07582661B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-fa66d20ba079433ba131edc6b98994fb |
| 출처 메모 | uspto-grants-2009_09 |