Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl 5-nitroisophthalate → Dimethyl 5-aminoisophthalate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl 5-nitroisophthalate | HCID 83316 | — |
| 반응물 | 4-Mercapto-5-aminoisophthalic acid hydrochloride | HCID 68993396 | — |
| 생성물 | Dimethyl 5-aminoisophthalate | HCID 66831 | — |
반응 단계
The AB2 monomer, 4-mercapto-5-aminoisophthalic acid hydrochloride, is synthesized in similar fashion, starting with catalytic hydrogenation of dimethyl 5-nitroisophthalate to form the corresponding amine, dimethyl-5-aminoisophthalate, which is then acetylated to protect the amino group. Dimethyl-5-aminoisophthalate is treated with thiocyanogen bromide (generated in-situ from bromine and ammonium thiocynate), and finally hydrolyzed to provide the desired monomer.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07582719B1 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-99526760e68845849d3b49efed3e0f55 |
| 출처 메모 | uspto-grants-2009_09 |