Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Dimethylaniline → 2,4-Dibromophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Dimethylaniline | HCID 949 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 2,4-Dibromophenol | HCID 12005 | — |
| 반응물 | Triphosgene | HCID 94429 | — |
| 생성물 | 2,4-Dibromophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838912 | — |
반응 단계
2,4-Dibromophenol (7.45 g, 29.6 mmol) was added as a solution in THF and dimethylaniline to a mixture of triphosgene (2.849 g, 9.6 mmol) in THF according to general procedure 3. Yield=6.09 g, 68%. m/z MH+=402.22. HPLC rt=12.49 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07589076B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-c035ca37c20646abba2c8df2711900b0 |
| 출처 메모 | uspto-grants-2009_09 |