Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Vinyltrimethylsilane → 4-Bromo-2-chloro-1-ethenylbenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Vinyltrimethylsilane | HCID 79102 | — |
| 반응물 | 4-Bromo-2-chloro-1-iodobenzene | HCID 2735547 | — |
| 반응물 | 4-Bromo-2-methyl-1-vinylbenzene | HCID 22598656 | — |
| 생성물 | 4-Bromo-2-chloro-1-ethenylbenzene | HCID 57842713 | 96% |
반응 단계
Using a procedure analogous to that used to prepare 30A, 4-bromo-2-chloro-1-iodobenzene (8 g, 25 mmol) was reacted with trimethyl(vinyl)silane in a pressure vessel at 160° C. for 1 h and worked up in a manner similar as in 30A to yield 61A (5.2 g, 96%) as an oil. 1H NMR (400 MHz, CDCl3) δ ppm 5.41 (d, J=11.86 Hz, 1 H) 7.02 (dd, J=17.36, 11.21 Hz, 1 H) 7.35 (dd, 1 H) 7.41 (d, 1 H) 7.52 (d, J=1.76 Hz, 1 H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07592331B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-2d460e143a7a461f97b4fc39ac894499 |
| 출처 메모 | uspto-grants-2009_09 |