Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzofuran-2-carboxylic acid → 1-[(2-Benzofuranylcarbonyl)amino]cyclohexanecarboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzofuran-2-carboxylic acid | HCID 10331 | — |
| 반응물 | Ethyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 11241228 | — |
| 생성물 | 1-[(2-Benzofuranylcarbonyl)amino]cyclohexanecarboxylic acid ethyl ester | HCID 57672902 | 80.3% |
반응 단계
3.11 g (15 mmol) of 1-aminocyclohexanecarboxylic acid ethyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride, and 2.43 g (15 mmol) of benzofuran-2-carboxylic acid was used instead of 3-furancarboxylic acid in the process according to Reference Example 15 to obtain 3.80 g (80%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829209B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-cd5431c4d51b45cdbf340916e98431de |
| 출처 메모 | uspto-grants-2014_09 |