Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(2-Ethyl-6-isopropylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2-Ethyl-6-isopropylphenyl isothiocyanate | HCID 144234 | — |
| 반응물 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(2-Ethyl-6-isopropylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one | HCID 85701469 | 64.9% |
반응 단계
The title compound was prepared by the procedure described in Example 1 using 10.25 g of 2-ethyl-6-isopropylphenyl-isothiocyanate, 7.68 g of sarcosine ethyl ester hydrochloride, 14.8 g of triethyl amine, and 200 mL of chloroform. Crystallization from diethyl ether/hexane mixture afforded the title compound (8.95 g) as a tan solid, m.p. 132°-134° C. Anal. Calcd. for C15H20N2O S: C, 65.18; H, 7.29; N, 10.13. Found: C, 65.11; H, 7.31; N, 10.05. Mass spectrum (PBEI, M.+) m/z 276.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05554607 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-7fe1c1abbd9c4663a47576548c5451dc |
| 출처 메모 | uspto-grants-1996_09 |