Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(2,6-Dimethylphenyl)-1-isopropyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2,6-Xylyl isothiocyanate | HCID 87976 | — |
| 반응물 | NoName_76 | HCID 414244 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(2,6-Dimethylphenyl)-1-isopropyl-2-thioxo-imidazolidin-4-one | HCID 4852838 | 49.2% |
반응 단계
The title compound was prepared by the procedure described in Example 45 using 16.3 g of 2,6-dimethylphenyl-isothiocyanate, 21.2 g of N-isopropyl glycine, 21.0 g of triethyl amine, and 300 mL of chloroform. Crystallization from ethanol afforded the title compound (12.9 g) as a white solid, m.p. 135°-137° C. Anal. Calcd. for. C14H18N2O S: C, 64.09; H, 6.92; N, 10.68. Found: C, 63.99; H, 6.72; N, 10.67. Mass spectrum (+FAB, I M+H]+) m/z 263.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05554607 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-ffb5a176460d46a090eac82120bfd0eb |
| 출처 메모 | uspto-grants-1996_09 |