Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalyl chloride → 4-[(4-Pyridyl)piperazin-1-yl]benzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 4-((4-Pyridyl)piperazin-1-yl)benzoic acid | HCID 18918300 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[(4-Pyridyl)piperazin-1-yl]benzoyl chloride | HCID 18918364 | — |
반응 단계
Oxalyl chloride (0.5 ml) was added to a stirred suspension of 4-((4-pyridyl)piperazin-1-yl)benzoic acid in dichloromethane (15 ml), followed by DMF (1 drop). The mixture was stirred for 2 hours and evaporated to dryness to give 4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride which was used immediately.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05556977 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-ebeb1141b56840efb7417eda6ec65051 |
| 출처 메모 | uspto-grants-1996_09 |