Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → HCID 58386753, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| 반응물 | 5-Fluoroindoline | HCID 2774463 | — |
| 반응물 | 6-Chloropyrazine-2-carboxylic acid | HCID 14500875 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 58386753 | HCID 58386753 | — |
반응 단계
0.18 g (1.1 mmol) 6-chloro-pyrazine-2-carboxylic acid, 0.15 g (1.1 mmol) 5-fluoro-2,3-dihydro-1H-indole, 0.31 mL (2.2 mmol) TEA in 3.0 mL DMF were mixed with 0.39 g (1.2 mmol) TBTU and stirred for 1 h at RT. The reaction mixture was mixed with water and stirred for 5 min. The precipitated solid was filtered, washed with water and dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829006B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-3174176a603a496082794b37e2e5e85e |
| 출처 메모 | uspto-grants-2014_09 |