Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2-aminoethyl)-1H-imidazo[4,5-c]quinolin-4-amine → n1-[2-(4-Amino-1h-imidazo[4,5-c]quinolin-1-yl)ethyl]-5-(2-oxoperhydrothieno[3,4-d]imidazol-4-yl)pentanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2-aminoethyl)-1H-imidazo[4,5-c]quinolin-4-amine | HCID 23512719 | — |
| 반응물 | N-Hydroxysuccinimido-d-biotin | HCID 129676281 | — |
| 생성물 | n1-[2-(4-Amino-1h-imidazo[4,5-c]quinolin-1-yl)ethyl]-5-(2-oxoperhydrothieno[3,4-d]imidazol-4-yl)pentanamide | HCID 23512652 | 75.2% |
반응 단계
Using the general method of Example 24, N-hydroxysuccinimidobiotin (0.6 g, 1.76 mmol) was reacted with 1-(2-aminoethyl)-1H-imidazo[4,5-c]quinolin-4-amine (0.4 g, 1.76 mmol) to provide 0.6 g of N1-[2-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]-5-(2-oxoperhydrothieno[3,4-d]imidazol-4-yl)pentanamide as a solid, m.p. 169° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07393859B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-2a7a774ae67a47aa8ee005c109bb6571 |
| 출처 메모 | uspto-grants-2008_07 |