참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 4-Benzyloxy-1-methyl-1H-indole-2-carboxylic acid | HCID 4777678 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 4-Benzyloxy-1-methyl-1H-indole-2-carbonyl chloride | HCID 22054872 | — |
반응 단계
To a stirred suspension of 4-benzyloxy-1-methyl-1H-indole-2-carboxylic acid (0.75 g) in benzene (5 mL) was added thionyl chloride (2.8 mL) in benzene (5 mL) followed by heated at 80° C. for 45 min. to give a clear orange solution. Evaporation to dryness gave 0.80 g of the title compound as an orange solid, which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07402604B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_07 |
|---|
| ORD ID | ord-9b7c208217634ef2acf1a25b4db3a35f |
|---|
| 출처 메모 | uspto-grants-2008_07 |
|---|
