Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2-Dimethylbutanoic acid → N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-2,2-dimethylbutanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2-Dimethylbutanoic acid | HCID 11684 | — |
| 반응물 | 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one | HCID 135594067 | — |
| 생성물 | N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-2,2-dimethylbutanamide | HCID 135752605 | — |
반응 단계
In analogy to the procedure for Example 58A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 78 mg (0.67 mmol) 2,2-dimethylbutanoic acid and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087605B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-035d364ace0543c9b021e13a63212a86 |
| 출처 메모 | uspto-grants-2006_08 |