참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Methyl 4-trimethylsilylethynylbenzoate | HCID 640161 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 4-ethynylbenzoate | HCID 640163 | — |
반응 단계
18.1 g (77.9 mmol) 4-trimethylsilanylethynyl-benzoic acid methyl ester are added to 400 mL MeOH, cooled down to 0° C. and charged with 3.24 g (23.4 mmol) K2CO3. The reaction mixture is stirred for 3 h, then the solvent is removed in vacuo and the resulting residue is purified by column chromatography (silica gel, hexane/TBME 10/1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08835472B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_09 |
|---|
| ORD ID | ord-de8bb91a8f924b978552978698209a98 |
|---|
| 출처 메모 | uspto-grants-2014_09 |
|---|
