Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,5-Dimethoxyphenol → 3-(3,5-Difluorophenyl)-1-benzofuran-4,6-diol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,5-Dimethoxyphenol | HCID 10383 | — |
| 반응물 | 2-Bromo-1-(3,5-difluorophenyl)ethanone | HCID 2778331 | — |
| 생성물 | 3-(3,5-Difluorophenyl)-1-benzofuran-4,6-diol | HCID 54591044 | 50% |
반응 단계
This compound was prepared using Method B from 3,5-dimethoxyphenol and 2-bromo-1-(3,5-difluorophenyl)ethanone: Yield 50% following procedures B.2, B.3 and B.5; m.p. 149-151° C.; IR 3373, 1629, 1507, 1359, 1255, 1157, 1123, 1031 cm−1; 1H-NMR (500 MHz, δ ppm, DMSO-d6) 10.08 (s, 1H), 9.45 (s, 1H), 8.02 (s, 1H), 7.49 (d, J=7.7 Hz, 2H), 7.13 (t, J=9.4 Hz, 1H), 6.43 (s, 1H), 6.28 (s, 1H); 13C-NMR (75 MHz, δ ppm, CD3OD) 164.3 (dd, J=244.8 Hz, 13.4 Hz), 160.4, 158.1, 153.5, 141.7, 137.8 (t, J=10.7 Hz), 122.6, 112.8 (dd, J=8.1 Hz, 17.6 Hz), 108.4, 102.6 (t, J=25.9 Hz), 99.4, 91.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08835659B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-7e9d15f317f14675b686424791b40cda |
| 출처 메모 | uspto-grants-2014_09 |