Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Decanal → Decanal Octreotide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Decanal | HCID 8175 | — |
| 반응물 | Octreotide | HCID 448601 | — |
| 용매 | Acetate | HCID 175 | — |
| 용매 | Sodium cyanoborohydride | HCID 5003444 | — |
| 생성물 | Decanal Octreotide | HCID 86614453 | — |
반응 단계
50 mg of octreotide was dissolved in 2 mL of 20 mM sodium cyanoborohydride (Mw 62.84, NaCNBH3) (2.51 mg) solution in 0.1 M acetate buffer at pH 5. 13.7 mg of Decanal (Mw 156.27) (OCT:DCL=1:2) was added by direct injection to the peptide solution. The reaction was allowed to proceed overnight at 4° C. The mixture was separated by centrifugation. The precipitated PAL-OCT was freeze-dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08840915B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-8559bdd4373e4da7aef99c9090ea4d3e |
| 출처 메모 | uspto-grants-2014_09 |