Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminophenol → 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminophenol | HCID 403 | — |
| 반응물 | Isopropylamine | HCID 6363 | — |
| 반응물 | 4-chloropyridine-2-carbonyl Chloride | HCID 11095146 | — |
| 반응물 | 4-Chloro-N-isopropyl-pyridine-2-carboxamide | HCID 22832083 | — |
| 생성물 | 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline | HCID 23614560 | — |
반응 단계
Entry 66: 4-Chloropyridine-2-carbonyl chloride was reacted with isopropylamine according to Method A2, Step 3b. The resulting 4-chloro-N-isopropyl-2-pyridinecarboxamide was reacted with 4-aminophenol according to Method A2, Step 4 to give 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline. According to Method C1a, 4-chloro-3-(trifluoromethyl)phenyl isocyanate was reacted with 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline to afford the urea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841330B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-c539b59d73c647f095d385aa6e2369be |
| 출처 메모 | uspto-grants-2014_09 |