Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl isothiocyanate → N-(2-(3-amino-6-(4-(isopropylsulfonyl)phenyl)pyrazine-2-carbonyl)hydrazinecarbonothioyl)ethanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl isothiocyanate | HCID 128851 | — |
| 반응물 | 3-Amino-6-(4-isopropylsulfonylphenyl)pyrazine-2-carbohydrazide | HCID 59471632 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | N-(2-(3-amino-6-(4-(isopropylsulfonyl)phenyl)pyrazine-2-carbonyl)hydrazinecarbonothioyl)ethanamide | HCID 59471667 | — |
반응 단계
A mixture of 3-amino-6-(4-isopropylsulfonylphenyl)pyrazine-2-carbohydrazide (100 mg, 0.2982 mmol), acetyl isothiocyanate (30.16 mg, 26.20 μL, 0.2982 mmol) and dry DCE (2.000 mL) were stirred at ambient temperature for 2 h and then concentrated in vacuo. Used directly in the next step without further purification; MS (ES+) 437.20
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841308B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-69524c100c5247dc8905c65244ff7dc6 |
| 출처 메모 | uspto-grants-2014_09 |