Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclohexanesulfonyl chloride → 5-((2-(1-(Cyclohexylsulfonyl)piperidin-4-yl)-2H-1,2,3-triazol-4-yl)methoxy)-2-(1H-tetrazol-1-yl)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclohexanesulfonyl chloride | HCID 237554 | — |
| 반응물 | 5-((2-(piperidin-4-yl)-2H-1,2,3-triazol-4-yl)methoxy)-2-(1H-tetrazol-1-yl)pyridine hydrochloride | HCID 68746624 | — |
| 생성물 | 5-((2-(1-(Cyclohexylsulfonyl)piperidin-4-yl)-2H-1,2,3-triazol-4-yl)methoxy)-2-(1H-tetrazol-1-yl)pyridine | HCID 25174424 | — |
반응 단계
The title compound was synthesized using Intermediate 15 and cyclohexanesulfonyl chloride in a similar manner as described in Example 39. 1H NMR (DMSO-d6): δ 10.08 (1H, s), 8.42 (1H, d), 8.01 (1H, d), 7.95 (1H, s), 7.86 (1H, dd), 3.52 (2H, s), 4.74 (1H, m), 3.68 (2H, m), 3.11 (3H, m) 2.51 (1H, m), 2.17 (2H, m) 1.92 (3H, m), 1.73 (1H, m), 1.23 (7H, m).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846675B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-a214a677167a46aa86d10b3bc754d56a |
| 출처 메모 | uspto-grants-2014_09 |