Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 1-benzyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| 반응물 | Benzylhydrazine dihydrochloride | HCID 146540 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-benzyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 9943096 | — |
반응 단계
Similar to Example 1, equimolar amounts of benzylhydrazine dihydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. The resulting oil was determined to be the named product by 1H-NMR (CDCl3, ppm): 1.35 t (3H); 2.44 s (3H); 2.45 s (3H); 4.38 a (2H); 5.25 s (2H); 7.08 d (2H); 7.29 m (3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087634B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-cdce1d85350340c0aefc14ad614d2d49 |
| 출처 메모 | uspto-grants-2006_08 |