Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Acetamidophenyl)boronic acid → N-{3-[6-(4-Isopropylpiperazin-1-yl)-5-methylpyridin-3-yl]phenyl}acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Acetamidophenyl)boronic acid | HCID 157274 | — |
| 반응물 | 1-(5-Bromo-3-methyl-pyridin-2-yl)-4-isopropyl-piperazine | HCID 67145961 | — |
| 생성물 | N-{3-[6-(4-Isopropylpiperazin-1-yl)-5-methylpyridin-3-yl]phenyl}acetamide | HCID 15951459 | — |
반응 단계
The title compound was prepared by a similar procedure to that described in Example 68, starting from 1-(5-bromo-3-methyl-pyridin-2-yl)-4-isopropyl-piperazine and 3-acetylaminophenylboronic acid. 1H NMR (300 MHz, CDCl3) δ 8.35 (d, 1H), 7.77 (s, 1H), 7.58 (d, 1H), 7.46 (d, 2H), 7.35 (t, 1H), 3.32 (t, 4H), 2.92-2.75 (m, 5H), 2.30 (s, 3H), 2.19 (s, 3H), 1.14 (d, 6H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846677B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-dbb795059eed4819aa1fb30aabb6b7a9 |
| 출처 메모 | uspto-grants-2014_09 |