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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 8318생성일: 2026년 10월 23일

1-Naphthalenesulfonyl chloride → 1-(1-Naphthylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride

https://huagongshe.com/ko/reaction/8318

반응식

참여 물질

역할이름HCID투입량
반응물1-Naphthalenesulfonyl chlorideHCID 66560—
반응물tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylateHCID 22015386—
생성물1-(1-Naphthylsulfonyl)-4-(1-piperazinyl)-1H-indole HydrochlorideHCID 10113364—

반응 단계

The title compound was prepared according 4-(4-boc-piperazinyl)-indole and naphthylsulfonylchloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.03 (br, 1 H), 8.63 (d, J=8 Hz, 1 H), 8.43 (d, J=8 Hz, 1 H), 8.34 (d, J=8 Hz, 1 H), 8.15–8.05 (m, 2 H), 7.80–7.65 (m, 3 H), 7.41 (d, J=8 Hz, 1 H), 7.18 (t, J=8 Hz, 1 H), 6.93 (d, J=5Hz, 1 H), 6.74 (d, J=8Hz, 1 H), 3.30–3.20 (m, 8 H); MS (ESI+) for m/z 392 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07087750B2
출처 데이터셋uspto-grants-2006_08
ORD IDord-0dd7577b1cbb45b08b04256982872821
출처 메모uspto-grants-2006_08