참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | N,N-Dimethylaniline | HCID 949 | — |
| 반응물 | Phthalic Anhydride | HCID 6811 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | Chlorobenzene | HCID 7964 | — |
| 생성물 | 2-[4-(Dimethylamino)benzoyl]benzoic acid | HCID 88937 | — |
반응 단계
A mixture of phthalic anhydride (30 g.), N,N-dimethylaniline (60.5 g.), aluminum chloride (60 g.) and chlorobenzene (180 g.) was heated (to 75° C.) during one hour, then cooled. Ice (500 ml.) was added, the chlorobenzene layer was separated and the chlorobenzene was steam distilled. Addition of base to a solution of the residue in dilute sulfuric acid afforded 2-(4-(dimethylamino)benzoyl)benzoic acid (IV: Y2 = Z4 = Z"5 = Z"6 = Z7 = H, Y'4 = (CH3)2N).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04096176 |
|---|
| 출처 데이터셋 | uspto-grants-1978_06 |
|---|
| ORD ID | ord-f88fec8b9caf4f29924de010ab035256 |
|---|
| 출처 메모 | uspto-grants-1978_06 |
|---|
